Recovery & RepairGrade B
BPC-157
A synthetic pentadecapeptide derived from a gastric protein, widely used for soft-tissue and gut healing on the strength of animal data.
- Regulatory status
- Not approved; FDA bulks list category 2
- Half-life
- ~4 hours (estimated)
- Route
- Subcutaneous, near-site injection, or oral
- Evidence
- Limited human trials or approved outside the US
Mechanism of action
Upregulates VEGF signaling and angiogenesis, modulates nitric oxide pathways, and promotes fibroblast migration in preclinical models.
Studied and reported uses
- Tendon and ligament injury
- Gut inflammation
- Post-surgical recovery
Dosing information
Reported research use250–500 mcg once or twice daily
Cycle4–8 weeks
Ranges are reported from literature and clinical labeling for reference only. They are not a dosing recommendation.
Side effects
- Injection-site irritation
- Mild nausea
- Long-term profile unknown
Research evidence
Preclinical
Consistent tendon/ligament healing effects in rodents.
Human data
No published randomized controlled trials.